Dozens of states across the US are pinning their hopes on contact tracing to control the spread of the coronavirus and enable regions to reopen without sparking major resurgences of the outbreak.
Alaska, California, Massachusetts, New York, and others are collectively hiring and training tens of thousands of people to interview infected patients, identify people they may have exposed, and convince everyone at risk to stay away from others for several weeks.
Contact tracing is a proven tool in containing outbreaks of highly infectious diseases. But this particular virus could pose significant challenges to tracing programs in the US, based on new studies and emerging evidence from initial efforts. Stubbornly high new infection levels in some areas, the continued shortage of tests, and American attitudes toward privacy could all hamstring the effectiveness of such programs.
The chief challenge with this coronavirus is its potential to spread exponentially: absent containment measures, every infected person on average will infect two or three others, according to most estimates (although some studies find it could be higher).
The goal of contact tracing, as well as social distancing, is to push down the number of people each infected person infects, creating an “effective reproduction number,” or Re, of 1 or less. At that point the number of new cases is flat or falling.
But contact tracers have to reach a significant portion of cases and contacts to really move those numbers.
A team in any given region would have to detect at least half of new symptomatic cases, and reach at least half the people they were in close contact with and encourage them to stay away from others, in order to reduce the transmission rate by 10% or more, according to a new model. (The work was published as a preprint on MedRxiv on May 8 but hasn’t been peer-reviewed yet.)
If they successfully detected 90% of symptomatic cases and reached 90% of their contacts—and tested all of them regardless of whether they had symptoms—it could reduce transmissions by more than 45%, the researchers found.
In other words, if social distancing in a given region had reduced infections per person from 2.6 to 1, this level of contact tracing could push it down to .55. Or the region could ease distancing measures by about half and keep infection levels constant.
“It gives us some room to be targeted and strategic in terms of the sorts of restrictions we have on business and commerce and social interactions,” says Joshua Salomon, a professor of medicine at Stanford and coauthor of the study.
Can we hit those kinds of figures? Salomon thinks it’s possible, but he adds that most of the nation doesn’t have the well-trained workers and data systems in place to achieve anything on that level yet. [Continue reading…]