Findings, music, and occasional reflections by Paul Woodward

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COVID-19’s stop-gap antibodies solution until vaccines and antivirals are ready

Johns Hopkins Bloomberg School of Public Health:

As novel coronavirus cases continue to mount globally, humanity can’t turn to its go-to infectious disease fixes: vaccines and drugs. At least not yet. A new vaccine might be at least 12 to 18 months away though new drug treatments will likely come sooner.

Arturo Casadevall, chair of the Department of Molecular Microbiology and Immunology at the Johns Hopkins Bloomberg School of Public Health, is helping organize a national effort to use antibodies from recovered COVID-19 patients for protection and treatments. In a March 13 Journal of Clinical Investigation article, Casadevall and Liise-anne Pirofski of the Albert Einstein College of Medicine proposed the stop-gap measure of using plasma (serum) from the blood of survivors until a vaccine and antiviral medications are available.

In this Q&A with Global Health NOW, Casadevall says clinical trials could begin in 3–4 weeks provided that they clear all the regulatory steps. If that happens, he anticipates widespread availability by early summer. [Continue reading…]

 

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