Attention to the Unseen

It is unclear how well masks work. People Image Studio/Shutterstock By Manal Mohammed, University of Westminster Although political leaders have closed borders in response to COVID-19, scientists are collaborating like never before. But the coronavirus (SARS-COV-2) is novel – and we don’t yet have all the facts about it. As a result, we may have to change our approach as new scientific data comes in. That doesn’t mean the science isn’t trustworthy – we will get the full picture over…

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Ed Yong writes: There’s a joke about immunology, which Jessica Metcalf of Princeton recently told me. An immunologist and a cardiologist are kidnapped. The kidnappers threaten to shoot one of them, but promise to spare whoever has made the greater contribution to humanity. The cardiologist says, “Well, I’ve identified drugs that have saved the lives of millions of people.” Impressed, the kidnappers turn to the immunologist. “What have you done?” they ask. The immunologist says, “The thing is, the immune…

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The Scientist reports: A new study is challenging the idea that younger children are somehow less susceptible to SARS-CoV-2 infection. Children under the age of five have been found to carry just as much, if not more, coronavirus in their noses and throats than older kids or adults. The results, published Thursday (July 30) in JAMA Pediatrics, tested 145 people for evidence of the virus’s RNA. After breaking their participants down into three age categories—younger children, older children, and adults—researchers…

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Philip Setel writes: How best to represent the true toll of the Covid-19 pandemic on human lives is an urgent matter. Though loss of life represents the clearest indicator, limited testing, inconsistencies in assigning the cause of death, and even political influence are creating uncertainty over how deaths are being counted and attributed (or not) to Covid-19. It’s simple, really: Limited testing gives a limited picture of confirmed Covid-19 cases and deaths. While many deaths show fairly clear evidence of…

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Zeynep Tufekci writes: I recently took a drive-through COVID-19 test at the University of North Carolina. Everything was well organized and efficient: I was swabbed for 15 uncomfortable seconds and sent home with two pages of instructions on what to do if I were to test positive, and what precautions people living with or tending to COVID-19 patients should take. The instructions included many detailed sections devoted to preventing transmission via surfaces, and also went into great detail about laundry,…

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Scientific American reports: COVID-19 triggers a strong immune response in most people. Yet several recent studies observed that the amounts of antibodies in those recovering from the virus appear to decline within a few months of infection. The findings set off a frenzy of speculation that immunity to the virus may not last long, throwing cold water on hopes for a vaccine. Many scientists say such worries are overblown, however. A June 18 Nature Medicine study conducted with a small…

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The New York Times reports: Five months after the coronavirus outbreak engulfed New York City, riders are still staying away from public transportation in enormous numbers, often because they are concerned that sharing enclosed places with strangers is simply too dangerous. But the picture emerging in major cities across the world suggests that public transportation may not be as risky as nervous New Yorkers believe. In countries where the pandemic has ebbed, ridership has rebounded in far greater numbers than…

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STAT reports: Never before have prospective vaccines for a pathogen entered final-stage clinical trials as rapidly as candidates for Covid-19. Just six months ago, when the death toll from the coronavirus stood at one and neither it nor the disease it caused had a name, a team of Chinese scientists uploaded its genetic sequence to a public site. That kicked off the record-breaking rush to develop vaccines — the salve that experts say could ultimately quell the pandemic. The colossal…

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Science Alerts reports: As deadly bacteria grow ever more resistant to modern antibiotics, some researchers have turned to ancient medical manuscripts for clues. And it looks like a medieval salve dating back 1,000 years might succeed where many modern antibiotics are starting to fail. The “ancientbiotic”, as the researchers are calling it, was found in one of the earliest known medical textbooks from medieval England, known as Bald’s Leechbook. While many of the remedies included in this tome have not…

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The Fish Site reports: A range of polysaccharides extracted from edible seaweed have been shown to at least match the efficacy of remdesivir, the current standard antiviral used to combat Covid-19, in new lab-based trials. The study, the results of which have recently been published in Cell Discovery, tests antiviral activity in three variants of heparin (heparin, trisulfated heparin, and a non-anticoagulant low molecular weight heparin) and two fucoidans (RPI-27 and RPI-28) extracted from the seaweed Saccharina japonica. All five…

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Derek Thompson writes: As a covid-19 summer surge sweeps the country, deep cleans are all the rage. National restaurants such as Applebee’s are deputizing sanitation czars to oversee the constant scrubbing of window ledges, menus, and high chairs. The gym chain Planet Fitness is boasting in ads that “there’s no surface we won’t sanitize, no machine we won’t scrub.” New York City is shutting down its subway system every night, for the first time in its 116-year history, to blast…

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Shannon Hall writes: As the new coronavirus continues to burn through populations, studies are beginning to shed light on its impact on infants. And so far the findings have been promising for parents and researchers alike. The initial data suggest that infants make up a small fraction of people who have tested positive for COVID-19. A Centers for Disease Control and Prevention study released in April reported 398 infections in children under one year of age—roughly 0.3 percent of all…

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