Attention to the Unseen

Allison Parshall writes: Alex Wiltschko began collecting perfumes as a teenager. His first bottle was Azzaro Pour Homme, a timeless cologne he spotted on the shelf at a T.J. Maxx department store. He recognized the name from Perfumes: The Guide, a book whose poetic descriptions of aroma had kick-started his obsession. Enchanted, he saved up his allowance to add to his collection. “I ended up going absolutely down the rabbit hole,” he said. More recently, as an olfactory neuroscientist for…

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Yasemin Saplakoglu writes: You’re on the vacation of a lifetime in Kenya, traversing the savanna on safari, with the tour guide pointing out elephants to your right and lions to your left. Years later, you walk into a florist’s shop in your hometown and smell something like the flowers on the jackalberry trees that dotted the landscape. When you close your eyes, the store disappears and you’re back in the Land Rover. Inhaling deeply, you smile at the happy memory….

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R. Douglas Fields writes: Neuroscientists, being interested in how brains work, naturally focus on neurons, the cells that can convey elements of sense and thought to each other via electrical impulses. But equally worthy of study is a substance that’s between them — a viscous coating on the outside of these neurons. Roughly equivalent to the cartilage in our noses and joints, the stuff clings like a fishing net to some of our neurons, inspiring the name perineuronal nets (PNNs)….

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Allison Whitten writes: When our phones and computers run out of power, their glowing screens go dark and they die a sort of digital death. But switch them to low-power mode to conserve energy, and they cut expendable operations to keep basic processes humming along until their batteries can be recharged. Our energy-intensive brain needs to keep its lights on too. Brain cells depend primarily on steady deliveries of the sugar glucose, which they convert to adenosine triphosphate (ATP) to…

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Nature reports: The brain is the body’s sovereign, and receives protection in keeping with its high status. Its cells are long-lived and shelter inside a fearsome fortification called the blood–brain barrier. For a long time, scientists thought that the brain was completely cut off from the chaos of the rest of the body — especially its eager defence system, a mass of immune cells that battle infections and whose actions could threaten a ruler caught in the crossfire. In the…

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