Bridget Ritz and Brandon Vaidyanathan write: When Paulo was an undergraduate, he was tasked with taking photographs of neurons. ‘A single cell,’ he came to notice, ‘it’s a whole universe.’ Looking at cells beneath a microscope is not unlike gazing at stars in the sky, Paulo realised. ‘We all know they are there, but until you see them with your own eyes, you don’t have that experience of awe, of wow.’ It was then, as he put it, that he…
David Spiegelhalter writes: Life is uncertain. None of us know what is going to happen. We know little of what has happened in the past, or is happening now outside our immediate experience. Uncertainty has been called the ‘conscious awareness of ignorance’ — be it of the weather tomorrow, the next Premier League champions, the climate in 2100 or the identity of our ancient ancestors. In daily life, we generally express uncertainty in words, saying an event “could”, “might” or…
Matthew Hutson writes: A while ago, I searched for a beard trimmer in my bedroom. I spent probably forty-five minutes looking in every likely location at least twice, and every unlikely location at least once. I swore up a storm; the trimmer never turned up. I’ve played similar games with pants. There’s a reason for the burgeoning market in electronic tags that track your belongings. Our poor memories can seem mystifying, especially when you consider animals. This time of year,…
The Guardian reports: World-leading scientists have called for a halt on research to create “mirror life” microbes amid concerns that the synthetic organisms would present an “unprecedented risk” to life on Earth. The international group of Nobel laureates and other experts warn that mirror bacteria, constructed from mirror images of molecules found in nature, could become established in the environment and slip past the immune defences of natural organisms, putting humans, animals and plants at risk of lethal infections. Although…
Emily R. Klancher Merchant writes: In the Operation Varsity Blues scandal of 2019, 50 wealthy parents were charged with trying to get their children into elite universities through fraudulent means. The story dramatically demonstrated the lengths to which some parents will go to ensure their children’s acceptance into places like Stanford, Yale, Georgetown, and USC. Actress Lori Loughlin and her husband, fashion designer Mossimo Giannulli, bribed athletic coaches to recruit their children for sports they did not play. Actress Felicity Huffman…
Ashish K. Jha, Matt Pottinger and Matthew McKnight write: President Richard M. Nixon’s bold 1969 decision to renounce biological weapons and spearhead a treaty to ban them helped contain the threat of a man-made pandemic for half a century. But our inheritance from Nixon is now fading. And in this age of synthetic biology, unless we act quickly to deter our adversaries from making and using bioweapons, we could face disaster in the near future. The nightmare of a biological…
Nature reports: Scientists around the world expressed disappointment and alarm as Republican Donald Trump won the final votes needed to secure the US presidency in the early hours of 6 November. Owing to Trump’s anti-science rhetoric and actions during his last term in office, many are now bracing for four years of attacks on scientists inside and outside the government. “In my long life of 82 years … there has hardly been a day when I felt more sad,” says…
Daniel W McShea and Gunnar O Babcock write: Why do rocks fall? Before Isaac Newton introduced his revolutionary law of gravity in 1687, many natural scientists and philosophers thought that rocks fell because falling was an essential part of their nature. For Aristotle, seeking the ground was an intrinsic property of rocks. The same principle, he argued, also explained why things like acorns grew into oak trees. According to this explanation, every physical object in the Universe, from rocks to…
Brian Klaas writes: On 30 October 1926, Henry and Mabel Stimson stepped off a steam train in Kyoto, Japan and set in motion an unbroken chain of events that, two decades later, led to the deaths of 140,000 people in a city more than 300 km away. The American couple began their short holiday in Japan’s former imperial capital by walking from the railway yard to their room at the nearby Miyako Hotel. It was autumn. The maples had turned…
Yasemin Saplakoglu writes: Around 2,500 years ago, Babylonian traders in Mesopotamia impressed two slanted wedges into clay tablets. The shapes represented a placeholder digit, squeezed between others, to distinguish numbers such as 50, 505 and 5,005. An elementary version of the concept of zero was born. Hundreds of years later, in seventh-century India, zero took on a new identity. No longer a placeholder, the digit acquired a value and found its place on the number line, before 1. Its invention…
Matt von Hippel writes: Data is almost always incomplete. Patients drop out of clinical trials and survey respondents skip questions; schools fail to report scores, and governments ignore elements of their economies. When data goes missing, standard statistical tools, like taking averages, are no longer useful. “We cannot calculate with missing data, just as we can’t divide by zero,” said Stef van Buuren, the professor of statistical analysis of incomplete data at the University of Utrecht. Suppose you are testing…
Science reports: In 2016, when the U.S. Congress unleashed a flood of new funding for Alzheimer’s disease research, the National Institute on Aging (NIA) tapped veteran brain researcher Eliezer Masliah as a key leader for the effort. He took the helm at the agency’s Division of Neuroscience, whose budget—$2.6 billion in the last fiscal year—dwarfs the rest of NIA combined. As a leading federal ambassador to the research community and a chief adviser to NIA Director Richard Hodes, Masliah would…
The editors of Scientific American write: In the November election, the U.S. faces two futures. In one, the new president offers the country better prospects, relying on science, solid evidence and the willingness to learn from experience. She pushes policies that boost good jobs nationwide by embracing technology and clean energy. She supports education, public health and reproductive rights. She treats the climate crisis as the emergency it is and seeks to mitigate its catastrophic storms, fires and droughts. In…
Biobots could one day be engineered to deliver drugs and clear up arterial plaque. Kriegman et al. 2020/PNAS, CC BY-SA By Peter A Noble, University of Washington and Alex Pozhitkov, Irell & Manella Graduate School of Biological Sciences at City of Hope Life and death are traditionally viewed as opposites. But the emergence of new multicellular life-forms from the cells of a dead organism introduces a “third state” that lies beyond the traditional boundaries of life and death. Usually, scientists…
Robin George Andrews writes: On September 16, 2023, the world began to rumble. A gargantuan rock-ice avalanche tumbled into the deep waters of a fjord in eastern Greenland, unleashing a megatsunami whose initial waves reached a height of 200 meters. The waves scoured the walls of the fjord before flowing into the open sea. Even for this avalanche-prone corner of Greenland, the collapse and subsequent megatsunami were shocking for their speed and ferocity. But what followed was considerably stranger. The…
Ross Andersen writes: Moni the chimpanzee was still new to the Dutch zoo when she lost her baby. The keepers hadn’t even known that she was pregnant. Neither did Zoë Goldsborough, a graduate student who had spent months jotting down every social interaction that occurred among the chimps, from nine to five, four days a week, for a study on jealousy. One chilly midwinter morning, Goldsborough found Moni sitting by herself on a high tree stump in the center of…