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Category: Science/mathematics

What’s next for Covid’s viral evolution

What’s next for Covid’s viral evolution

Nature reports: As the world sped towards a pandemic in early 2020, evolutionary biologist Jesse Bloom gazed into the future of SARS-CoV-2. Like many virus specialists at the time, he predicted that the new pathogen would not be eradicated. Rather, it would become endemic — the fifth coronavirus to permanently establish itself in humans, alongside four ‘seasonal’ coronaviruses that cause relatively mild colds and have been circulating in humans for decades or more. Bloom, who is based at the Fred…

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Where did ‘weird’ Omicron come from?

Where did ‘weird’ Omicron come from?

Science reports: Since South African scientists announced last week they had identified an unsettling new variant of SARS-CoV-2, the world has anxiously awaited clues about how it might change the trajectory of the pandemic. But as big a mystery—if less urgent—is where and how Omicron evolved, and what lessons its emergence holds for avoiding future dangerous variants. Omicron clearly did not develop out of one of the earlier variants of concern, such as Alpha or Delta. Instead, it appears to…

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Charting changes in a pathogen’s genome yields clues about its past and hints about its future

Charting changes in a pathogen’s genome yields clues about its past and hints about its future

A virus’s genes hold a record of where it’s traveled, and when. imaginima/E+ via Getty Images By Claire Guinat, Swiss Federal Institute of Technology Zurich; Etthel Windels, Swiss Federal Institute of Technology Zurich, and Sarah Nadeau, Swiss Federal Institute of Technology Zurich More than 250 million people worldwide have tested positive for SARS-CoV-2, usually after a diagnostic nose swab. Those swabs aren’t trash once they’ve delivered their positive result, though. For scientists like us they carry additional valuable information about…

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Omicron risks infecting vaccinated people but may not cause them severe illness

Omicron risks infecting vaccinated people but may not cause them severe illness

The Wall Street Journal reports: The Omicron variant of the Covid-19 virus could lead to more infections among vaccinated people, according to several scientists, but some said there were reasons to believe the shots would protect against severe disease. While the new variant might evade the antibodies generated in reaction to the vaccines, the virus will likely remain vulnerable to immune cells that destroy it once it enters the body, said Ugur Sahin, co-founder of BioNTech SE, which sells a…

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It looks like Omicron causes milder illness – is this how COVID becomes endemic?

It looks like Omicron causes milder illness – is this how COVID becomes endemic?

AP Photo/Denis Farrell By Hamish McCallum, Griffith University These are very early days in terms of our understanding the Omicron variant. What is known is that it has a large number of mutations, particularly in the spike protein and it appears to be rapidly spreading in specific parts of the world. Very early indications from Africa suggest it does not cause particularly severe disease (though the World Health Organization has urged caution given the limited data available). At this point,…

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Interesting research, but no, we don’t have living, reproducing robots

Interesting research, but no, we don’t have living, reproducing robots

John Timmer writes: Scientists on Monday announced that they’d optimized a way of getting mobile clusters of cells to organize other cells into smaller clusters that, under the right conditions, could be mobile themselves. The researchers call this process “kinematic self-replication,” although that’s not entirely right—the copies need help from humans to start moving on their own, are smaller than the originals, and the copying process grinds to a halt after just a couple of cycles. So, of course, CNN…

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How the Omicron variant rattled the world in one week

How the Omicron variant rattled the world in one week

The Wall Street Journal reports: Over coffee at his office on Tuesday, Tulio de Oliveira, director of South Africa’s Center for Epidemic Response and Innovation, let a colleague in on a secret. “There’s something going on,” he told Alex Sigal, a virologist growing coronaviruses at a South African laboratory. “They’ve found a variant they’ve never seen before.” For days, case numbers in the nation had been rising rapidly. Puzzled lab technicians had been getting back Covid-19 tests that were positive,…

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These ‘living robots’ self-replicate — and it’s not terrifying

These ‘living robots’ self-replicate — and it’s not terrifying

The Daily Beast reports: You might have missed the debut of the Xenobots last year when the world was falling apart, but they made quite a splash in the science and tech community. These Pac-Man-shaped synthetic organisms designed by supercomputers can organize into larger groups and be programmed to fulfill specific functions. They’re certainly not robots in the traditional sense, but they’re also too artificial to qualify as typical living organisms. They’re part cell, part machine, and completely one-of-a-kind. As…

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How dangerous Omicron is, won’t be known for weeks

How dangerous Omicron is, won’t be known for weeks

Science reports: At 7.30 a.m. on Wednesday, Kristian Andersen, an infectious disease researcher at Scripps Research in San Diego, received a message on Slack: “This variant is completely insane.” Andrew Rambaut of the University of Edinburgh was reacting to a new SARS-CoV-2 genome sequence found in three samples collected in Botswana on 11 November and one picked up a week later in a traveler from South Africa to Hong Kong. Andersen looked at the data and then replied: “Holy shit—that…

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What we need to understand about the Omicron variant

What we need to understand about the Omicron variant

Ashish Jha asks: How worrisome is Omicron? There are three key questions that help scientists understand how consequential any variant might be. The first question is whether the variant is more transmissible than the current, prevalent Delta strain? Second, does it cause more severe disease? And third, will it render our immune defenses — from vaccines and prior infections — less effective (a phenomenon known as immune escape)? On transmissibility, the data, while early, look worrisome. This new variant appears…

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What impossible meant to Richard Feynman

What impossible meant to Richard Feynman

Paul J. Steinhardt writes: Impossible! The word resonated throughout the large lecture hall. I had just finished describing a revolutionary concept for a new type of matter that my graduate student, Dov Levine, and I had invented. The Caltech lecture room was packed with scientists from every discipline across campus. The discussion had gone remarkably well. But just as the last of the crowd was filing out, there arose a familiar, booming voice and that word: “Impossible!” I could have…

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First known Covid case was vendor at Wuhan market, scientist claims

First known Covid case was vendor at Wuhan market, scientist claims

The New York Times reports: A scientist who has pored over public accounts of early Covid-19 cases in China reported on Thursday that an influential World Health Organization inquiry had most likely gotten the early chronology of the pandemic wrong. The new analysis suggests that the first known patient sickened with the coronavirus was a vendor in a large Wuhan animal market, not an accountant who lived many miles from it. The report, published on Thursday in the prestigious journal…

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Who said science and art were two cultures?

Who said science and art were two cultures?

Kevin Berger writes: On a May evening in 1959, C.P. Snow, a popular novelist and former research scientist, gave a lecture before a gathering of dons and students at the University of Cambridge, his alma mater. He called his talk “The Two Cultures and the Scientific Revolution.” Snow declared that a gulf of mutual incomprehension divided literary intellectuals and scientists. “The non-scientists have a rooted impression that the scientists are shallowly optimistic, unaware of man’s condition,” Snow said. “On the…

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Men are just as emotional as women, study suggests

Men are just as emotional as women, study suggests

Alison Escalante writes: It is not a compliment to call someone “emotional.” We incorrectly see emotion as the opposite of the “rational” or “effective,” even though neuroscientists have long known that emotion is what drives intelligent thought. Now scientists have just revealed another area where we get emotion completely wrong. Despite centuries of stereotypes, a new study finds that men are just as emotional as women. Men have the same ups and downs, highs and lows as women do. And…

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Earth’s first continents may have appeared three-quarters of a billion years earlier than previously thought

Earth’s first continents may have appeared three-quarters of a billion years earlier than previously thought

Inside Science reports: Earth’s first continents may have emerged from the oceans roughly 750 million years earlier than previously thought, rising from the seas in a manner completely unlike modern continents. These early masses of solid rock may have floated buoyantly atop magma welling up from below, a new study finds. Unlike any other known planet, Earth possesses both continents and oceans on its surface. The emergence of land from sea greatly influenced Earth’s atmosphere, oceans, climate and proliferation of…

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An idea about safety that keeps putting us in danger

An idea about safety that keeps putting us in danger

Tim Requarth writes: Remember March of 2020, before masks? Back then, as we became aware that the coronavirus was circulating around the country at an alarming clip, packed up our offices, and pulled our kids out of in-person school, the nation’s top experts urged us not to bother covering our nose and mouths. Among the complex reasons for the hesitation was a simple one: distrust of the public. “I worry that if people put on masks, then they’ll think, OK,…

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