Attention to the Unseen

Jordana Cepelewicz writes: For a few months last year, Nigel Goldenfeld and Sergei Maslov, a pair of physicists at the University of Illinois, Urbana-Champaign, were unlikely celebrities in their state’s COVID-19 pandemic response — that is, until everything went wrong. Their typical areas of research include building models for condensed matter physics, viral evolution and population dynamics, not epidemiology or public health. But like many scientists from diverse fields, they joined the COVID-19 modeling effort in March, when the response…

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Daniel P. Oran and Eric J. Topol write: Jan. 24 marks the one-year anniversary of a momentous but largely unnoticed event in the history of the Covid-19 pandemic: the first published report of an individual infected with the novel coronavirus who never developed symptoms. This early confirmation of asymptomatic infection should have set off alarm bells and profoundly altered our response to the gathering storm. But it did not. One year later we are still paying the price for this…

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STAT reports: Three-quarters of Covid-19 patients still have at least one symptom six months after first falling ill, researchers who followed hospital patients in China reported Friday. The new findings suggest symptoms linger longer and in a higher proportion of patients than previously thought. The largest and longest analysis to date of post-Covid recovery also warns that some patients’ antibody levels fell sharply, raising concern that while waiting for a return to full health, they could be reinfected with the…

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STAT reports: In an extraordinary time, British health authorities are taking extraordinary measures to beat back Covid-19. But some experts say that, in doing so, they are also taking a serious gamble. In recent days, the British have said they will stretch out the interval between the administration of the two doses required for Covid-19 vaccines already in use — potentially to as long as three months, instead of the recommended three or four weeks. And they have said they…

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Jay Caspian Kang writes: On March 10th, the day before Tom Hanks announced that he had tested positive for Covid-19, I drove my three-year-old daughter to her day care in Berkeley, California. The drive took us up College Avenue, where white-haired professors huddled at sidewalk café tables; we passed the fraternity houses where students gathered on the lawns. Just a few blocks from my daughter’s school, there’s a coffee shop with a clientele split equally between students and senior citizens….

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Zeynep Tufekci writes: A new variant of the coronavirus is spreading across the globe. It was first identified in the United Kingdom, where it is rapidly spreading, and has been found in multiple countries. Viruses mutate all the time, often with no impact, but this one appears to be more transmissible than other variants—meaning it spreads more easily. Barely one day after officials announced that America’s first case of the variant had been found in the United States, in a…

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James Hamblin writes: The newly discovered coronavirus had killed only a few dozen people when Feixiong Cheng started looking for a treatment. He knew time was of the essence: Cheng, a data analyst at the Cleveland Clinic, had seen similar coronaviruses tear through China and Saudi Arabia before, sickening thousands and shaking the global economy. So, in January, his lab used artificial intelligence to search for hidden clues in the structure of the virus to predict how it invaded human…

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Donald G. McNeil Jr. reports: At what point does a country achieve herd immunity? What portion of the population must acquire resistance to the coronavirus, either through infection or vaccination, in order for the disease to fade away and life to return to normal? Since the start of the pandemic, the figure that many epidemiologists have offered has been 60 to 70 percent. That range is still cited by the World Health Organization and is often repeated during discussions of…

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STAT reports: Unprecedented collaborative efforts in vaccine development have culminated in multiple vaccines being tested in advanced clinical trials all in less than one year since global leaders understood we were in the midst of a global pandemic. One is now being given to health care workers, and another will soon follow. As the first Covid-19 vaccines are being distributed in the United States and in other countries around the world, the main question now on many minds is, “Are…

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Ed Yong writes: In Fall of 2019, exactly zero scientists were studying COVID‑19, because no one knew the disease existed. The coronavirus that causes it, SARS‑CoV‑2, had only recently jumped into humans and had been neither identified nor named. But by the end of March 2020, it had spread to more than 170 countries, sickened more than 750,000 people, and triggered the biggest pivot in the history of modern science. Thousands of researchers dropped whatever intellectual puzzles had previously consumed…

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