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Category: Science/mathematics

Vaccines could affect how the coronavirus evolves – but that’s no reason to skip your shot

Vaccines could affect how the coronavirus evolves – but that’s no reason to skip your shot

Vaccines against COVID-19 are the safest – and fastest – way to prevent the spread of variants. Luis Alvarez/ DigitalVision via Getty Images By Andrew Read, Penn State Takeaways A 2015 paper on a chicken virus showed vaccines could enable more deadly variants to spread – in chickens. But that outcome is rare. Only a minority of human and animal vaccines have affected the evolution of a virus. In most of those cases, evolution didn’t increase the severity of the…

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Having Covid once confers much greater immunity than a vaccine — but no infection parties, please

Having Covid once confers much greater immunity than a vaccine — but no infection parties, please

Science reports: The natural immune protection that develops after a SARS-CoV-2 infection offers considerably more of a shield against the Delta variant of the pandemic coronavirus than two doses of the Pfizer-BioNTech vaccine, according to a large Israeli study that some scientists wish came with a “Don’t try this at home” label. The newly released data show people who once had a SARS-CoV-2 infection were much less likely than vaccinated people to get Delta, develop symptoms from it, or become…

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Show me the data

Show me the data

Zeynep Tufekci writes: Who should get vaccine booster shots and when? Can vaccinated people with a breakthrough infection transmit the virus as easily as unvaccinated people? How many people with breakthrough infections die or get seriously ill, broken down by age and underlying health conditions? Confused? It’s not you. It’s the fog of pandemic, in which inadequate data hinders a clear understanding of how to fight a stealthy enemy. To overcome the fog of war, the Prussian general and military…

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How a cheap antidepressant emerged as a promising Covid-19 treatment

How a cheap antidepressant emerged as a promising Covid-19 treatment

Vox reports: Since Covid-19 patients started showing up at clinics and hospitals a year and a half ago, doctors and researchers have been hard at work trying to figure out how to treat them. Most drugs and treatments haven’t panned out, producing either no results or small ones in large-scale clinical trials. Many of the few that work are expensive and difficult to administer. Hydroxychloroquine, enthusiastically endorsed by President Trump last year, has been shown to have no measurable benefits….

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How I escaped my troubles through science

How I escaped my troubles through science

Subodh Patil writes: We’ve all felt the need. To just drop whatever loads we’re bearing, retreating to some private realm where our worldly concerns fade into oblivion. Freed from responsibilities, anxieties, hurts, and other miscellaneous burdens, if only transiently. My earliest recollection of the urge must’ve been when I was around 5. My mother was colorfully scolding me the way Indian mothers do, for something I probably did but nevertheless felt unjustly prosecuted for. Turning to the sky beyond the…

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A lucky few seem ‘resistant’ to Covid-19. Scientists want to know why

A lucky few seem ‘resistant’ to Covid-19. Scientists want to know why

STAT reports: Her husband collapsed just before reaching the top of the stairs in their small one-bedroom house in São Paulo, Brazil. Frantic, Thais Andrade grabbed the portable pulse oximeter she had purchased after hearing that a low oxygen reading could be the first sign of the novel coronavirus. Erik’s reading was hovering eight points lower than it had that morning. He also looked feverish. “When he hit 90% [on the oximeter], I said we can’t wait anymore,” Andrade recalled….

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Why the coronavirus has changed as it has, and what it means going forward

Why the coronavirus has changed as it has, and what it means going forward

STAT reports: It’s impossible to say how the coronavirus will continue to evolve. Those changes, after all, are a result of random mutations. But there are some fundamental principles that explain why the virus has morphed as it has, principles that could guide our understanding of its ongoing evolution — and what that means for our future with the pathogen. The great fear is that nature could spit out some new variant that completely saps the power of vaccines and…

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How will the coronavirus evolve?

How will the coronavirus evolve?

Dhruv Khullar writes: In 1988, Richard Lenski, a thirty-one-year-old biologist at UC Irvine, started an experiment. He divided a population of a common bacterium, E. coli, into twelve flasks. Each flask was kept at thirty-seven degrees Celsius, and contained an identical cocktail of water, glucose, and other nutrients. Each day, as the bacteria replicated, Lenski transferred several drops of each cocktail to a new flask, and every so often he stored samples away in a freezer. His goal was to…

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Massive new analysis confirms just how many Covid cases are truly asymptomatic

Massive new analysis confirms just how many Covid cases are truly asymptomatic

Science Alert reports: Within months of SARS-CoV-2’s emergence as a global catastrophe it was becoming clear that many who spread the disease did so unwittingly, experiencing not so much as a tickle in their throat to alert them of the danger within. Distinguishing those who are truly asymptomatic from those who are simply yet to show signs of the virus has made it hard to calculate a precise figure on the risks of succumbing to the illness. Now an analysis…

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The woman who brought us the world

The woman who brought us the world

Alice Dragoon writes: Had Virginia Tower Norwood listened to her high school guidance counselor, she would have become a librarian. Her aptitude test showed a remarkable facility with numbers, and in 1943, he could think of no better way for a young woman to put such skills to use. Luckily, Norwood didn’t suffer from the same lack of imagination. The salutatorian of her Philadelphia high school class, she had long been devouring logic puzzles and putting the slide rule her…

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Your vaccinated immune system is ready for breakthroughs

Your vaccinated immune system is ready for breakthroughs

Katherine J. Wu writes: A new dichotomy has begun dogging the pandemic discourse. With the rise of the über-transmissible Delta variant, experts are saying you’re either going to get vaccinated, or going to get the coronavirus. For some people—a decent number of us, actually—it’s going to be both. Coronavirus infections are happening among vaccinated people. They’re going to keep happening as long as the virus is with us, and we’re nowhere close to beating it. When a virus has so…

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We may finally know why the delta variant of coronavirus is so infectious

We may finally know why the delta variant of coronavirus is so infectious

Live Science reports: People infected with the delta variant of the novel coronavirus may be carrying more than a thousand times more virus particles and may test positive two days earlier than those infected with the original SARS-CoV-2, according to an early new study. The study has not been peer reviewed and looked at only a small number of cases in China, but if the results can be confirmed, they may explain, at least in part, why the delta variant…

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Coexisting with the coronavirus

Coexisting with the coronavirus

Katherine S. Xue writes: In the spring of 1846, a Dutch physician named Peter Ludwig Panum arrived on the Faroe Islands, a volcanic chain about two hundred miles northwest of Scotland. He found the Faroes to be a harsh and unforgiving place. The islands’ eight thousand inhabitants, who were Danish subjects at that time, spent their days outdoors, buffeted by sea winds, fishing and tending sheep. The conditions, Panum wrote, were unlikely “to prolong the lives of the inhabitants.” And…

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India’s true pandemic death toll likely to be well over 3 million, new study finds

India’s true pandemic death toll likely to be well over 3 million, new study finds

The New York Times reports: The number of people who have died in the coronavirus pandemic in India so far is likely to exceed three million — nearly 10 times the official Covid-19 death toll — making it one of the worst human tragedies in the nation’s history, according to a new study. In a comprehensive examination of the true toll of the pandemic in the sprawling nation of 1.4 billion, the Center for Global Development, a Washington research institute,…

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Ivermectin Covid-19 scandal shows how vulnerable science is to fraud

Ivermectin Covid-19 scandal shows how vulnerable science is to fraud

James Heathers and Gideon Meyerowitz-Katz write: Most scientists assume they will never come across a single case of fraud in their careers, and so even the thought of checking calculations in reviewable papers, re-running analyses, or checking if experimental protocols were properly deployed is deemed unnecessary. Worse, the accompanying raw data and analytical code often needed to forensically analyze a paper are not routinely published, and performing this kind of stringent review is often considered to be a hostile act,…

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Is it time to assume that health research is fraudulent until proven otherwise?

Is it time to assume that health research is fraudulent until proven otherwise?

Richard Smith, former editor of the British Medical Journal, writes: Health research is based on trust. Health professionals and journal editors reading the results of a clinical trial assume that the trial happened and that the results were honestly reported. But about 20% of the time, said Ben Mol, professor of obstetrics and gynaecology at Monash Health, they would be wrong. As I’ve been concerned about research fraud for 40 years, I wasn’t that surprised as many would be by…

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