Inside the nucleus, genes’ activity may depend on their location
Jordana Cepelewicz writes: The nucleus of a cell has something in common with a cardboard box full of kittens: People get so fascinated by the contents that they overlook the container. The nucleus itself is often treated as no more than a featureless membranous bag for holding the vitally dynamic genetic material. Yet in fact it has specialized parts and an internal architecture of its own, and scientists have long speculated that precisely how the DNA positions itself with respect…